54 Wimpole St - Office Space for Lease, Marylebone, London W1G 8YJ
54 Wimpole Street is a historic office building located in the prestigious Marylebone district of London’s West End. Originally built circa 1770 and recently renovated in 2026, this traditional masonry property offers high-quality office accommodation within one of Central London’s most sought-after professional locations.
The property provides 1,111 sq ft of available first-floor office and medical accommodation, offering a versatile workspace suitable for professional practices, healthcare occupiers and businesses seeking a characterful Central London address. The accommodation benefits from excellent natural light, open-plan areas, partitioned offices, a kitchen, secure storage, air conditioning and central heating.
Positioned within the renowned Harley Street and Marylebone medical district, 54 Wimpole Street benefits from a prestigious setting surrounded by established medical, professional, retail and hospitality occupiers, while offering convenient access to Regent’s Park, Oxford Circus and Marylebone transport connections.
Location
54 Wimpole Street is located in Marylebone, London W1G 8YJ, within the City of Westminster. The property is situated within the heart of the West End, close to Harley Street, Portland Place and Marylebone Village.
Marylebone is a highly desirable Central London commercial location, recognised for its blend of medical institutions, professional services, independent retailers and premium dining destinations. The area provides a prestigious working environment with excellent access to neighbouring districts including Mayfair, Fitzrovia and Oxford Circus.
For further details or to make a booking, please contact Fraser Bond.
Property Details
Property Type: Office / Medical Accommodation
Address: 54 Wimpole Street, London W1G 8YJ
Borough: City of Westminster
Location: Marylebone, London
Region: Greater London
Submarket: Marylebone
Submarket Cluster: London West End
Location Type: Central Business District (CBD)
Total Building Size: 4,929 sq ft NIA
Available Space: 1,111 sq ft
Maximum Contiguous Space: 1,111 sq ft
Available Floor: First Floor
Building Floors: 5 floors
Typical Floorplate: 1,081 sq ft
Construction: Traditional Masonry
Year Built: 1770
Renovated: 2026
Building Grade: 3 Star Office
Tenure: Leasehold
Lease Type: Internal Repairing and Insuring (IRI)
Furnishing: Not provided
Available Accommodation
The available accommodation comprises:
First Floor Office / Medical Space: 1,111 sq ft
The accommodation provides flexible workspace suitable for professional offices, healthcare practices, consultants and businesses requiring a prestigious Marylebone address.
Rent & Service Charge
Asking Rent: £99.00 per sq ft
Service Type: Internal Repairing and Insuring (IRI)
Service Charge: Not specified
Amenities & Features
Recently renovated historic office building
Excellent natural light
Open-plan workspace
Partitioned offices
Air conditioning
Central heating
Secure storage facilities
Kitchen facilities
Security system
Basement storage
Period architectural character
Prime Marylebone location
Leasing Highlights
Prestigious Wimpole Street address within Marylebone’s professional district.
1,111 sq ft first-floor office and medical accommodation available.
Suitable for healthcare providers, consultants and professional businesses.
Located close to Harley Street, one of London’s leading medical districts.
Recently renovated accommodation combining historic character with modern functionality.
Excellent transport connections to Oxford Circus, Regent’s Park and Marylebone Station.
Connectivity & Transport
54 Wimpole Street benefits from excellent transport links, with Regent’s Park Underground Station approximately 8 minutes’ walk away and Great Portland Street Underground Station around 9 minutes’ walk away. Baker Street and Bond Street stations are also within easy reach, providing access across Central London.
London Marylebone Station is approximately 0.8 miles away, while London City Airport is around 10.5 miles from the property.
For further details or to make a booking, please contact Fraser Bond.
